Concepedia

The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging

Cheng Luo, Egon Urgard, Tõnu Vooder, Andres Metspalu

Medical Hypotheses · 2011 · 115 citations · 38 references

DOI

Concepts

References

38

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.6K citations · Full text

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Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial

Robert S. Bresalier, Robert S. Sandler, Hui Quan et al. · New England Journal of Medicine · 2005 · 2.5K citations · Full text

, , +8

Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

Akira Kobayashi, Moon-Il Kang, Hiromi Okawa et al. · Molecular and Cellular Biology · 2004 · 2.2K citations · Full text

, , +17

Lipid mediator class switching during acute inflammation: signals in resolution

Bruce D. Levy, Clary B. Clish, Birgitta Schmidt et al. · Nature Immunology · 2001 · 1.4K citations

, , +14

Inducible cyclooxygenase may have anti-inflammatory properties

Derek W. Gilroy, Paul Colville‐Nash, Dean Willis et al. · Nature Medicine · 1999 · 1.2K citations

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