Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

Akira Kobayashi, Moon-Il Kang, Hiromi Okawa, +5

Molecular and Cellular Biology

Molecular BiologyRedox BiologyOxidative StressTranscription Factor Nrf2Proteomics +16

Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers

Nobunao Wakabayashi, Albena T. Dinkova‐Kostova, W. David Holtzclaw, +5

Proceedings of the National Academy of Sciences

Molecular BiologyRedox BiologyOxidant StressOxidative StressSignaling Pathway +17

Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1

Akira Kobayashi, Moon-Il Kang, Yoriko Watai, +4

Molecular and Cellular Biology

Molecular BiologyRedox BiologyOxidative StressUbiquitination ActivityCell Regulation +15

Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer

Balasundaram Padmanabhan, Kit I. Tong, Tsutomu Ohta, +7

Molecular Cell

MedicineKeap1 Activity ProvokedMolecular BiologyCancer GenomicsStructural Basis +6

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

Moon-Il Kang, Akira Kobayashi, Nobunao Wakabayashi, +2

Proceedings of the National Academy of Sciences

Differential Responses of the Nrf2-Keap1 System to Laminar and Oscillatory Shear Stresses in Endothelial Cells

Tomonori Hosoya, Atsushi Maruyama, Moon-Il Kang, +5

Journal of Biological Chemistry

Effects of Meal Timing on Postprandial Glucose Metabolism and Blood Metabolites in Healthy Adults

Masaki Takahashi, Mamiho Ozaki, Moon-Il Kang, +7

Nutrients

Tryptophan metabolism regulates proliferative capacity of human pluripotent stem cells

Shota Someya, Shugo Tohyama, K Kameda, +16

iScience

Microwave-Based Reaction Screening: Tandem Retro-Diels–Alder/Diels–Alder Cycloadditions of<i>o</i>-Quinol Dimers

Suwei Dong, Katharine J. Cahill, Moon-Il Kang, +6

The Journal of Organic Chemistry

Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1

Balasundaram Padmanabhan, Maria Scharlock, Kit I. Tong, +6

Acta Crystallographica Section F Structural Biology and Crystallization Communications