Moon-Il Kang

Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

Akira Kobayashi, Moon-Il Kang, Hiromi Okawa et al. · Molecular and Cellular Biology · 2004 · 2.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers

Nobunao Wakabayashi, Albena T. Dinkova‐Kostova, W. David Holtzclaw et al. · Proceedings of the National Academy of Sciences · 2004 · 966 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1

Akira Kobayashi, Moon-Il Kang, Yoriko Watai et al. · Molecular and Cellular Biology · 2005 · 930 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer

Balasundaram Padmanabhan, Kit I. Tong, Tsutomu Ohta et al. · Molecular Cell · 2006 · 731 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

Moon-Il Kang, Akira Kobayashi, Nobunao Wakabayashi et al. · Proceedings of the National Academy of Sciences · 2004 · 532 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13