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Utilization of Natural Fucosylated Oligosaccharides by Three Novel α- <scp>l</scp> -Fucosidases from a Probiotic <i>Lactobacillus casei</i> Strain

Jesús Rodríguez‐Díaz, Vicente Monedero, Marı́a J. Yebra

Applied and Environmental Microbiology · 2010 · 99 citations · 9 references

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Abstract

Three putative α-L-fucosidases encoded in the Lactobacillus casei BL23 genome were cloned and purified. The proteins displayed different abilities to hydrolyze natural fucosyloligosaccharides like 2'-fucosyllactose, H antigen disaccharide, H antigen type II trisaccharide, and 3'-, 4'-, and 6'-fucosyl-GlcNAc. This indicated a possible role in the utilization of oligosaccharides present in human milk and intestinal mucosa.

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