In Vitro Fermentation of Breast Milk Oligosaccharides by <i>Bifidobacterium infantis</i> and <i>Lactobacillus gasseri</i>

Abstract

It has been proposed that human milk oligosaccharides (HMO) function as a prebiotic for bifidobacteria, yet this activity has not been adequately investigated. In this study, Bifidobacterium infantis was shown to ferment purified HMO as a sole carbon source, while another gut commensal, Lactobacillus gasseri, did not ferment HMO. Our results support the hypothesis that HMO selectively amplify bacterial populations in the infant intestine.