Concepedia

Brain plasmin enhances APP α‐cleavage and Aβ degradation and is reduced in Alzheimer's disease brains

María Dolores Ledesma, Jorge Santos Da Silva, Katleen Crassaerts, André Delacourte, Bart De Strooper, Carlos G. Dotti

EMBO Reports · 2000 · 212 citations · 25 references

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25

Functional rafts in cell membranes

Kai Simons, Elina Ikonen · Nature · 1997 · 9.7K citations

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Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

Chutima Srimaroeng, Jennifer Perry Cecile, Ramsey Walden et al. · Cellular Physiology and Biochemistry · 2013 · 3K citations · Full text

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Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

Mikael Simons, Patrick Keller, Bart De Strooper et al. · Proceedings of the National Academy of Sciences · 1998 · 1.2K citations

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Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

Sven Lammich, Elżbieta Kojro, Rolf Postina et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

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Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

Joseph D. Buxbaum, Kang-Nian Liu, Yuxia Luo et al. · Journal of Biological Chemistry · 1998 · 916 citations · Full text

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