Concepedia

Amyloid Clearance

Amyloid Clearance is a cellular proteostasis mechanism that specifically mediates the recognition, degradation, and removal of amyloid aggregates through proteasomal, autophagic, and chaperone-mediated pathways.

954

Publications

92.5K

Citations

5.6K

Authors

1.3K

Institutions

Publications per year

2017–2026

349

Parents

Publications

954

Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease

Kwasi G. Mawuenyega, Wendy Sigurdson, Vitaliy Ovod et al. · Science · 2010 · 2.1K citations · Full text

, , +13

Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

Suzanne E. Hickman, Elizabeth Allison, Joseph El Khoury · Journal of Neuroscience · 2008 · 1.3K citations · Full text

, , +17

Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

Joseph M. Castellano, Jungsu Kim, Floy R. Stewart et al. · Science Translational Medicine · 2011 · 1.2K citations

, , +9

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

Jeffrey J. Iliff, Hedok Lee, Mei Yu et al. · Journal of Clinical Investigation · 2013 · 1.2K citations · Full text

, , +16

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Paige E. Cramer, John R. Cirrito, Daniel W. Wesson et al. · Science · 2012 · 1K citations

, , +17

1–5 of 954

Authors

5.6K

  1. DM
    David M. Holtzman

    Washington University in St. Louis, United States

    23 publications · 7.7K citations

    23

    h-index

  2. GB
    Guojun Bu

    Mayo Clinic in Florida, United States

    19 publications · 3.9K citations

    18

    h-index

  3. JR
    John R. Cirrito

    Hope Center for Neurological Disorders, United States

    13 publications · 4K citations

    13

    h-index

  4. RJ
    Randall J. Bateman

    Washington University in St. Louis, United States

    11 publications · 5.1K citations

    11

    h-index

  5. BT
    Bradley T. Hyman

    Massachusetts General Hospital, United States

    11 publications · 2.5K citations

    11

    h-index

1–5 of 5.6K

Institutions

1.3K

  1. Washington University in St. Louis

    St Louis, United States

    35 h-index

    163 publications

    66.4K citations

  2. Harvard University

    Cambridge, United States

    31 h-index

    148 publications

    24K citations

  3. Hope Center for Neurological Disorders

    St Louis, United States

    30 h-index

    153 publications

    48.4K citations

  4. University of Kentucky

    Lexington, United States

    22 h-index

    95 publications

    6.2K citations

  5. Massachusetts General Hospital

    Boston, United States

    22 h-index

    126 publications

    18.9K citations

  6. Brigham and Women's Hospital

    Boston, United States

    21 h-index

    70 publications

    15K citations

  7. University College London

    London, United Kingdom

    19 h-index

    81 publications

    13.5K citations

  8. Biomedical Research Networking Center on Neurodegenerative Diseases

    Madrid, Spain

    16 h-index

    69 publications

    5.6K citations

1–8 of 1.3K

Venues

  1. Journal of Neuroscience

    55 publications · 11.1K citations

    51

    h-index

  2. Journal of Alzheimer s Disease

    JAD · 53 publications · 3.6K citations

    34

    h-index

  3. Journal of Biological Chemistry

    JBC · 37 publications · 5.7K citations

    32

    h-index

  4. PubMed

    Repository · 32 publications · 1.8K citations

    22

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 3.8K citations

    19

    h-index

1–5