Concepedia

Protein Quality Control

Protein Quality Control is a cellular surveillance system that identifies, repairs, or degrades misfolded, damaged, or aberrant proteins to maintain proteostasis and ensure proper protein function within the cell.

545

Publications

41.7K

Citations

2.6K

Authors

760

Institutions

Publications per year

2017–2026

202

Parents

Children

Publications

545

The dTAG system for immediate and target-specific protein degradation

Behnam Nabet, Justin M. Roberts, Dennis L. Buckley et al. · Nature Chemical Biology · 2018 · 1.2K citations · Full text

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Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6α and XBP1

Keisuke Yamamoto, Takashi Sato, Toshie Matsui et al. · Developmental Cell · 2007 · 1K citations · Full text

, , +11

Misfolded proteins partition between two distinct quality control compartments

Daniel Kaganovich, Ron R. Kopito, Judith Frydman · Nature · 2008 · 963 citations · Full text

, , +12

The nucleolus functions as a phase-separated protein quality control compartment

Frédéric Frottin, Florian Schueder, Shivani Tiwary et al. · Science · 2019 · 530 citations · Full text

, , +15

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

Martin Gamerdinger, Parvana Hajieva, A Murat Kaya et al. · The EMBO Journal · 2009 · 518 citations · Full text

, , +15

1–5 of 545

Authors

2.6K

  1. BB
    Bernd Bukau

    Heidelberg University, Germany

    10 publications · 859 citations

    10

    h-index

  2. DH
    Dieter H. Wolf

    University of Stuttgart, Germany

    9 publications · 871 citations

    9

    h-index

  3. RG
    Richard G. Gardner

    University of Washington, United States

    9 publications · 880 citations

    9

    h-index

  4. AM
    Axel Mogk

    Heidelberg University, Germany

    8 publications · 734 citations

    8

    h-index

  5. DC
    Douglas Cyr

    University of North Carolina at Chapel Hill, United States

    8 publications · 1.2K citations

    8

    h-index

1–5 of 2.6K

Institutions

760

  1. National Institutes of Health

    Bethesda, United States

    17 h-index

    53 publications

    5K citations

  2. Heidelberg University

    Heidelberg, Germany

    17 h-index

    94 publications

    9K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    31 publications

    6.9K citations

  4. Stanford University

    Stanford, United States

    12 h-index

    48 publications

    7K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    12 h-index

    38 publications

    3.3K citations

  6. University of California San Diego

    San Diego, United States

    12 h-index

    60 publications

    8.1K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    12 h-index

    42 publications

    6.8K citations

  8. Johns Hopkins University

    Baltimore, United States

    11 h-index

    50 publications

    4.3K citations

1–8 of 760

Venues

  1. Journal of Biological Chemistry

    JBC · 44 publications · 4.1K citations

    34

    h-index

  2. Molecular Biology of the Cell

    MBC · 28 publications · 2.6K citations

    23

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 2.1K citations

    19

    h-index

  4. Molecular Cell

    14 publications · 2K citations

    14

    h-index

  5. PLoS ONE

    14 publications · 601 citations

    14

    h-index

1–5