John R. Cirrito

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

Yaming Wang, Marina Cella, Kaitlin Mallinson et al. · Cell · 2015 · 1.7K citations · Full text

Inflammation, Neurodegenerative Diseases, Alzheimer's Disease +12

Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

Jae-Eun Kang, Miranda M. Lim, Randall J. Bateman et al. · Science · 2009 · 1.5K citations · Full text

Sleep Disorders, Neurochemical Biomarkers, Neuroinflammation +21

Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo

John R. Cirrito, Kelvin A. Yamada, Mary Beth Finn et al. · Neuron · 2005 · 1.3K citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Molecular Neuroscience +8

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Paige E. Cramer, John R. Cirrito, Daniel W. Wesson et al. · Science · 2012 · 1K citations · Full text

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

Adam W. Bero, Ping Yan, Jee Hoon Roh et al. · Nature Neuroscience · 2011 · 879 citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Alzheimer's Disease +6