Concepedia

The Size of the Proteasomal Substrate Determines Whether Its Degradation Will Be Mediated by Mono- or Polyubiquitylation

Nitzan Shabek, Yifat Herman-Bachinsky, Samuel Buchsbaum, Oded Lewinson, Mahmood Haj‐Yahya, Mirva Hejjaoui, Hilal A. Lashuel, Thomas Sommer, Ashraf Brik, Aaron Ciechanover

Molecular Cell · 2012 · 165 citations · 44 references

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44

Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

Ana María Cuervo, Leonidas Stefanis, Ross A. Fredenburg et al. · Science · 2004 · 2K citations

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Recognition of the polyubiquitin proteolytic signal

Julia S. Thrower, Laura Hoffman, Martin Rechsteiner et al. · The EMBO Journal · 2000 · 1.7K citations · Full text

, , +6

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

Vincent Chau, John W. Tobias, Andreas Bachmair et al. · Science · 1989 · 1.5K citations

, , +14

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

J.T. Bolin, David J. Filman, David A. Matthews et al. · Journal of Biological Chemistry · 1982 · 745 citations · Full text

, , +17

Proteasome subunit Rpn13 is a novel ubiquitin receptor

Koraljka Husnjak, Suzanne Elsasser, Naixia Zhang et al. · Nature · 2008 · 659 citations · Full text

, , +12