J.T. Bolin

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

J.T. Bolin, David J. Filman, David A. Matthews et al. · Journal of Biological Chemistry · 1982 · 745 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Dihydrofolate Reductase: X-ray Structure of the Binary Complex with Methotrexate

D.A. Matthews, Richard A. Alden, J.T. Bolin et al. · Science · 1977 · 320 citations

Life Sciences, Biochemistry, Biophysics +17

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

David A. Matthews, J.T. Bolin, Jane M. Burridge et al. · Journal of Biological Chemistry · 1985 · 272 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. II. Environment of bound NADPH and implications for catalysis.

David J. Filman, J.T. Bolin, David A. Matthews et al. · Journal of Biological Chemistry · 1982 · 232 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex.

David A. Matthews, Richard A. Alden, J.T. Bolin et al. · Journal of Biological Chemistry · 1978 · 225 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15