Increased urinary 15-F_2t-isoprostane concentrations in patients with non-ischaemic congestive heart failure: a marker of oxidative stress

Abstract

Urinary 15-F2t-isoprostane concentrations increased in proportion to the severity of CHF in patients. This may be caused by increased 15-F2t-isoprostane production. These findings suggest that urinary 15-F2t-isoprostane may be a marker of morbidity as well as oxidative stress in patients with CHF.