Concepedia

Reductive Stress

Reductive Stress is a metabolic condition characterized by an excessive accumulation of reducing equivalents, such as NADH and reduced glutathione, that disrupts normal cellular redox homeostasis by impairing the cell’s ability to maintain appropriate oxidation-reduction balance.

156

Publications

10.6K

Citations

971

Authors

329

Institutions

Publications per year

2017–2026

86

Parents

Publications

156

Complementation of mitochondrial electron transport chain by manipulation of the NAD <sup>+</sup> /NADH ratio

Denis V. Titov, Valentin Cracan, Russell P. Goodman et al. · Science · 2016 · 516 citations · Full text

, , +17

Human αB-Crystallin Mutation Causes Oxido-Reductive Stress and Protein Aggregation Cardiomyopathy in Mice

Namakkal S. Rajasekaran, Patrice M. Connell, Elisabeth Christians et al. · Cell · 2007 · 433 citations · Full text

, , +7

Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress

William M. Oldham, Clary B. Clish, Yi Yang et al. · Cell Metabolism · 2015 · 374 citations · Full text

, , +17

Lactate Limits T Cell Proliferation via the NAD(H) Redox State

William J. Quinn, Jing Jiao, Tara TeSlaa et al. · Cell Reports · 2020 · 352 citations · Full text

, , +17

Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes

Thomas L. Dawson, Gregory J. Gores, A. L. Nieminen et al. · American Journal of Physiology-Cell Physiology · 1993 · 341 citations

, , +17

1–5 of 156

Authors

971

  1. NS
    Namakkal S. Rajasekaran

    University of Utah, United States

    11 publications · 924 citations

    11

    h-index

  2. IJ
    Ivor J. Benjamin

    University of Utah, United States

    8 publications · 975 citations

    8

    h-index

  3. JJ
    John J. Lemasters

    University of North Carolina at Chapel Hill, United States

    5 publications · 783 citations

    5

    h-index

  4. AT
    Armida Torreggiani

    University of Bologna, Italy

    5 publications · 111 citations

    5

    h-index

  5. CC
    Chryssostomos Chatgilialoglu

    Institute of Organic Synthesis and Photoreactivity, Italy

    4 publications · 98 citations

    4

    h-index

1–5 of 971

Institutions

329

  1. University of Utah

    Salt Lake City, United States

    15 h-index

    73 publications

    8.6K citations

  2. Harvard University

    Cambridge, United States

    12 h-index

    41 publications

    7.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    38 publications

    8.1K citations

  4. Center for Systems Biology

    Boston, United States

    6 h-index

    15 publications

    3.5K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    6 h-index

    23 publications

    4K citations

  6. Cornell University

    Ithaca, United States

    6 h-index

    25 publications

    1K citations

  7. University of Alabama at Birmingham

    Birmingham, United States

    6 h-index

    29 publications

    964 citations

  8. Broad Institute

    Cambridge, United States

    5 h-index

    22 publications

    5.1K citations

1–8 of 329

Venues

  1. Redox Biology

    6 publications · 350 citations

    7

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 417 citations

    6

    h-index

  3. Journal of Biological Chemistry

    JBC · 5 publications · 244 citations

    5

    h-index

  4. Antioxidants and Redox Signaling

    ARS · 5 publications · 313 citations

    5

    h-index

  5. Nature Communications

    4 publications · 549 citations

    4

    h-index

1–5