William M. Oldham

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

Thomas Bertero, William M. Oldham, Katherine A. Cottrill et al. · Journal of Clinical Investigation · 2016 · 423 citations · Full text

Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress

William M. Oldham, Clary B. Clish, Yi Yang et al. · Cell Metabolism · 2015 · 368 citations · Full text

Reductive Stress, Metabolic Syndrome, Biochemistry +11

Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy

Thomas Bertero, William M. Oldham, Eloïse M. Grasset et al. · Cell Metabolism · 2018 · 360 citations · Full text

Tumor Biology, Biochemistry, Medicine +8

High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics

Maurizio Pellegrino, Adam Sciambi, Sebastian Treusch et al. · Genome Research · 2018 · 261 citations · Full text

Engineering, Mixed-phenotype Acute Leukemia, Droplet Microfluidics +24

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

Anita K. Mehta, Emily Cheney, Christina Hartl et al. · Nature Cancer · 2020 · 239 citations · Full text

Breast Oncology, Medicine, Immunology +8