Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas, Kui Lei, Rebecca L. Hurley et al. · Genes & Development · 2004 · 1.4K citations · Full text

Medicine, Cell Biology, Oncology +17

Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1

Isaam Ben Sahra, Claire Regazzetti, Guillaume Robert et al. · Cancer Research · 2011 · 620 citations

Medicine, Oncology, Pharmacology +17

<i>PUMA</i> mediates the apoptotic response to p53 in colorectal cancer cells

Jian Yu, Zhenghe Wang, Kenneth W. Kinzler et al. · Proceedings of the National Academy of Sciences · 2003 · 561 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Daidzein Is a More Bioavailable Soymilk Isoflavone than Is Genistein in Adult Women

Xia Xu, Huei‐Ju Wang, Patricia A. Murphy et al. · Journal of Nutrition · 1994 · 514 citations

Agriculture, Nutrition, Nutritional Sciences +4

REDD1, a Developmentally Regulated Transcriptional Target of p63 and p53, Links p63 to Regulation of Reactive Oxygen Species

Leif W. Ellisen, Kate D Ramsayer, Cory M. Johannessen et al. · Molecular Cell · 2002 · 480 citations · Full text

Life Sciences, Genetics, Molecular Biology +14