Concepedia

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nagalingam R. Sundaresan, Prabhakaran Vasudevan, Lei Zhong, Gene Kim, Sadhana Samant, Vishwas Parekh, Vinodkumar B. Pillai, Madhu Gupta, Mahesh P. Gupta, Mahesh P. Gupta

Nature Medicine · 2012 · 475 citations · 36 references

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36

HEART DISEASE AND STROKE STATISTICS–2014 UPDATE: A REPORT FROM THE AMERICAN HEART ASSOCIATION

Talicia Tarver · Journal of Consumer Health on the Internet · 2014 · 5.6K citations · Full text

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Heart Disease and Stroke Statistics—2010 Update

Donald M. Lloyd‐Jones, Robert J. Adams, Todd M. Brown et al. · Circulation · 2009 · 5.6K citations

, , +10

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Martin Holzenberger, Joëlle Dupont, Bertrand Ducos et al. · Nature · 2002 · 2.1K citations · Full text

, , +12

Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase

Haim Cohen, Christine Miller, Kevin J. Bitterman et al. · Science · 2004 · 1.9K citations

, , +16

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Matthew D. Hirschey, Tadahiro Shimazu, Eric S. Goetzman et al. · Nature · 2010 · 1.7K citations · Full text

, , +14