Mahesh P. Gupta - Concepedia

Author

Mahesh P. Gupta

University of Chicago ORCID

Also Known As

Gupta, M., M Gupta, M P Gupta, M. Gupta, M. P. Gupta, M.P Gupta, M.P. Gupta, Madhu Gupta, Mahesh Gupta, Mahesh P Gupta

194

Publications

9.8K

Citations

H-Index

112

Concepts

All Affiliations

University of Chicago University of Illinois Chicago Indiana University – Purdue University Indianapolis Advocate Children's Hospital Richard L. Roudebush VA Medical Center

About

Mahesh P. Gupta is an author at University of Chicago specializing in medicine, cell biology, and cell signaling.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	28	38	3.2K
2	Natural Sciences	8	8	709
3	Health Sciences	6	6	182
4	Engineering	2	2	49
5	Public Health	1	1	65

Mahesh P. Gupta

Publications

7.8K

Citations

H-Index

Page 1

	Year	Citations
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice Nagalingam R. Sundaresan, Madhu Gupta, Gene Kim, Journal of Clinical Investigation	2009	982
SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70 Nagalingam R. Sundaresan, Sadhana Samant, Vinodkumar B. Pillai, Molecular and Cellular Biology Only SirtuinStress-mediated Cell DeathApoptosisCell DeathShort Form	2008	531
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun Nagalingam R. Sundaresan, Prabhakaran Vasudevan, Lei Zhong, Nature Medicine Cardiac MuscleCardiomyopathyMolecular PhysiologySignaling PathwayCardiac Hypertrophy	2012	470
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3 Vinodkumar B. Pillai, Sadhana Samant, Nagalingam R. Sundaresan, Nature Communications	2015	429
Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway Vinodkumar B. Pillai, Nagalingam R. Sundaresan, Gene Kim, Journal of Biological Chemistry	2009	422
SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress Sadhana Samant, Hannah J. Zhang, Zhigang Hong, Molecular and Cellular Biology Cell DeathMitochondrial BiologyOpa1 ActivityOxidative StressCell Signaling	2013	419
Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion and Reduced Sir2α Deacetylase Activity Jyothish B. Pillai, Ayman Isbatan, Shin Imai, Journal of Biological Chemistry	2005	386
The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy Nagalingam R. Sundaresan, Vinodkumar B. Pillai, Don Wolfgeher, Science Signaling	2011	345
Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling Osama Abo Alrob, Sowndramalingam Sankaralingam, Cary Ma, Cardiovascular Research	2014	212
SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β Nagalingam R. Sundaresan, Samik Bindu, Vinodkumar B. Pillai, Molecular and Cellular Biology InflammationTgf-β1 SignalingFibrosisSignaling PathwayCell Regulation	2015	194

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