Lei Zhong

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

Lei Zhong, Agustina D’Urso, Debra Toiber et al. · Cell · 2010 · 980 citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +10

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

Carlos Sebastián, Bernadette Zwaans, Dafne M. Silberman et al. · Cell · 2012 · 651 citations · Full text

Histone Modifications, Epigenetic Change, Histone Deacetylase Sirt6 +16

Loss of epigenetic information as a cause of mammalian aging

Jae-Hyun Yang, Motoshi Hayano, Patrick Griffin et al. · Cell · 2023 · 564 citations · Full text

Chromatin, Developmental Biology, Aging +8

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nagalingam R. Sundaresan, Prabhakaran Vasudevan, Lei Zhong et al. · Nature Medicine · 2012 · 470 citations · Full text

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +9

SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling

Debra Toiber, Fabian Erdel, Karim Bouazoune et al. · Molecular Cell · 2013 · 379 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +8