Carlos Sebastián

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

Lei Zhong, Agustina D’Urso, Debra Toiber et al. · Cell · 2010 · 980 citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +10

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

Hong Jiang, Saba Khan, Yi Wang et al. · Nature · 2013 · 684 citations · Full text

Inflammation, Transcriptional Regulation, Protein Secretion +10

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

Carlos Sebastián, Bernadette Zwaans, Dafne M. Silberman et al. · Cell · 2012 · 651 citations · Full text

Histone Modifications, Epigenetic Change, Histone Deacetylase Sirt6 +16

SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling

Debra Toiber, Fabian Erdel, Karim Bouazoune et al. · Molecular Cell · 2013 · 379 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +8

SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b

Sita Kugel, Carlos Sebastián, Julien Fitamant et al. · Cell · 2016 · 316 citations · Full text

Tumor Biology, Pancreatic Cancer, Medicine +4