Loss of epigenetic information as a cause of mammalian aging

Jae-Hyun Yang, Motoshi Hayano, Patrick Griffin, +61

Cell

ChromatinDevelopmental BiologyAgingLongevityGenetics +6

Rif1 is a global regulator of timing of replication origin firing in fission yeast

Motoshi Hayano, Yutaka Kanoh, Seiji Matsumoto, +3

Genes & Development

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsCell Cycle +21

Senescence‐associated secretory phenotype promotes chronic ocular graft‐vs‐host disease in mice and humans

Mio Yamane, Shinri Sato, Eisuke Shimizu, +13

The FASEB Journal

Loss of Epigenetic Information as a Cause of Mammalian Aging

Jae-Hyun Yang, Motoshi Hayano, Patrick Griffin, +57

SSRN Electronic Journal

ChromatinDevelopmental BiologyAgingLongevityGenetics +6

Mrc1 Marks Early-Firing Origins and Coordinates Timing and Efficiency of Initiation in Fission Yeast

Motoshi Hayano, Yutaka Kanoh, Seiji Matsumoto, +1

Molecular and Cellular Biology

GeneticsMolecular BiologyCell CycleCell RegulationAutophagy +14

Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast

Seiji Matsumoto, Michie Shimmoto, Naoko Kakusho, +5

Cell Cycle

Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation

Seiji Matsumoto, Motoshi Hayano, Yutaka Kanoh, +1

The Journal of Cell Biology

Replication Fork IntegrityMolecular RegulationMolecular BiologyCell CycleDna Replication Initiation +16

Dynamic stem cell selection safeguards the genomic integrity of the epidermis

Tomoki Kato, Nan Liu, Hironobu Morinaga, +11

Developmental Cell

Lineage PlasticityCell LineageDevelopmental BiologyMedicineGenetics +7

Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals

Jae-Hyun Yang, Patrick Griffin, Daniel L. Vera, +22

Dna DamageAgingEpigenetic ChangeGeneticsBiogerontology +16

DNA Break-Induced Epigenetic Drift as a Cause of Mammalian Aging

Motoshi Hayano, Jae-Hyun Yang, Michael S. Bonkowski, +38

Dna DamageAgingAnti-agingEpigenetic ChangeGenetics +22