Pharmacokinetics and Antitumor Efficacy of XMT-1001, a Novel, Polymeric Topoisomerase I Inhibitor, in Mice Bearing HT-29 Human Colon Carcinoma Xenografts - Concepedia

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Pharmacokinetics and Antitumor Efficacy of XMT-1001, a Novel, Polymeric Topoisomerase I Inhibitor, in Mice Bearing HT-29 Human Colon Carcinoma Xenografts

44

Citations

29

References

2012

Year

Mark D. Walsh, Suzan K. Hanna, Jeremy Sen, Sumit Rawal, Carolina Cabral, Alex Yurkovetskiy, Robert J. Fram, Timothy B. Lowinger, William C. Zamboni

Clinical Cancer Research

Abstract

XMT-1001 provides an extended systemic and tumor exposure of conjugated drug and shows improved antitumor effect compared with CPT-11.

References

	Year	Citations

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