Timothy B. Lowinger

Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1

Toshiki Murata, Mitsuyuki Shimada, Sachiko Sakakibara et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 171 citations · Full text

Molecular Pharmacology, Drug Target, Medicine +8

A selective novel low‐molecular‐weight inhibitor of I<i>κ</i>B kinase‐<i>β</i> (IKK‐<i>β</i>) prevents pulmonary inflammation and shows broad anti‐inflammatory activity

Karl Ziegelbauer, Florian Gantner, Nicholas W. Lukacs et al. · British Journal of Pharmacology · 2005 · 145 citations · Full text

Asthma, Antifibrotic Therapy, Inflammatory Lung Disease +23

Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents

Toshiki Murata, Mitsuyuki Shimada, Sachiko Sakakibara et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 118 citations · Full text

Inflammation, Medicinal Chemistry, Anti-inflammatory +11

A Polymer-Based Antibody–Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy

Alexander V. Yurkovetskiy, Mao Yin, Natalya D. Bodyak et al. · Cancer Research · 2015 · 99 citations

Engineering, Smart Polymer, Biomedical Engineering +20

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Roger A. Smith, J A Barbosa, Cheri L. Blum et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 85 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Drug Target +12