Concepedia

Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance

Hiroyuki Takaba, Yasuyuki Morishita, Yoshihiko Tomofuji, Lynett Danks, Takeshi Nitta, Noriko Komatsu, Tatsuhiko Kodama, Hiroshi Takayanagi

Cell · 2015 · 378 citations · 43 references

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43

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

Mark S. Anderson, Emily S. Venanzi, Ludger Klein et al. · Science · 2002 · 2.5K citations

, , +17

T cell tolerance by clonal elimination in the thymus

John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations

, , +14

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

Stephan Sanders, Michael T. Murtha, Abha R. Gupta et al. · Nature · 2012 · 2.2K citations

, , +12

Foxp3<sup>+</sup>CD25<sup>+</sup>CD4<sup>+</sup> natural regulatory T cells in dominant self‐tolerance and autoimmune disease

Shimon Sakaguchi, Masahiro Ono, Ruka Setoguchi et al. · Immunological Reviews · 2006 · 1.5K citations · Full text

, , +17

Positional cloning of the APECED gene

Kentaro Nagamine, Pärt Peterson, Hamish S. Scott et al. · Nature Genetics · 1997 · 1.4K citations

, , +10