Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

Kojiro Sato, Ayako Suematsu, Kazuo Okamoto, +9

The Journal of Experimental Medicine

T-regulatory CellImmunologyT CellsOrthopaedic SurgeryInflammatory Arthritis +19

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling

Mitsunobu R. Kano, Younsoo Bae, Caname Iwata, +12

Proceedings of the National Academy of Sciences

Tgf-beta InhibitorsEngineeringBiomedical EngineeringTumor BiologyNanomedicine +18

Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance

Hiroyuki Takaba, Yasuyuki Morishita, Yoshihiko Tomofuji, +5

Cell

Thymic ProgramImmunogeneticsImmune ToleranceAutoimmune DiseaseAdaptive Immune System +8

Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis

Masataka Asagiri, Toshitake Hirai, Toshihiro Kunigami, +14

Science

Regulation of osteoclast differentiation and function by the CaMK-CREB pathway

Kojiro Sato, Ayako Suematsu, Tomoki Nakashima, +11

Nature Medicine

SclerostinDevelopmental BiologySignal TransductionBone Morphogenic ProteinOsteoarthritis +8

Integral role of Noxa in p53-mediated apoptotic response

Tsukasa Shibue, Kiyoshi Takeda, Eri Oda, +7

Genes & Development

The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma

Naoko Yamauchi, Akira Watanabe, Michiyo Hishinuma, +12

Modern Pathology

HepatologyOncogenic AgentOncofetal ProteinGlycobiologyHistopathology +9

Autophagy Is Activated by TGF-β and Potentiates TGF-β–Mediated Growth Inhibition in Human Hepatocellular Carcinoma Cells

Kunihiko Kiyono, Hiroshi Suzuki, Hironori Matsuyama, +5

Cancer Research

MitophagyImmunologyCell DeathCell ProliferationAutophagy Genes +20

VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B–PDGFRβ signaling

Mitsunobu R. Kano, Yasuyuki Morishita, Caname Iwata, +5

Journal of Cell Science

Long-term Risk of Malignancy in Branch-Duct Intraductal Papillary Mucinous Neoplasms

Hiroki Oyama, Minoru Tada, Kaoru Takagi, +20

Gastroenterology

Surgical OncologyTumoral PathologyMedicineSurgical PathologyPathology +5