Immunological Tolerance
Immunological Tolerance is a physiological state of the immune system characterized by specific non-responsiveness to an antigen that would otherwise elicit an immune response, brought about by active mechanisms such as deletion, inactivation or regulation of antigen-reactive lymphocytes that prevent destructive reactions against self or other non-harmful antigens.
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‘Actively Acquired Tolerance’ of Foreign Cells
R. E. Billingham, L Brent, P. B. Medawar · Nature · 1953 · 3.1K citations
T cell tolerance by clonal elimination in the thymus
John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
Paweł Kisielow, Horst Blüthmann, Uwe D. Staerz et al. · Nature · 1988 · 1.7K citations
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Harvard University
Cambridge, United States
41 h-index
234 publications
39.8K citations
National Institutes of Health
Bethesda, United States
27 h-index
98 publications
10.6K citations

Walter and Eliza Hall Institute of Medical Research
Melbourne, Australia
26 h-index
104 publications
8K citations
Scripps Health
San Diego, United States
24 h-index
78 publications
7.2K citations
National Institute of Allergy and Infectious Diseases
Bethesda, United States
23 h-index
72 publications
7.9K citations
Massachusetts General Hospital
Boston, United States
22 h-index
97 publications
8.2K citations
University of Pennsylvania
Philadelphia, United States
21 h-index
88 publications
6.8K citations
Scripps Clinic
La Jolla, United States
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56 publications
8.6K citations
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JI · 188 publications · 10.3K citations
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Repository · 183 publications · 7.2K citations
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EJI · 87 publications · 3.8K citations
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