Concepedia

Periodic, Partial Inhibition of IκB Kinase β-Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis

Kathleen M. Gillooly, Mark A. Pattoli, Tracy L. Taylor, Laishun Chen, Lihong Cheng, Kurt R. Gregor, Gena S. Whitney, Vojkan Susulic, Scott H. Watterson, James Kempson,

Journal of Pharmacology and Experimental Therapeutics · 2009 · 26 citations · 31 references

DOI

Concepts

References

31

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

Yi Chen, Cristina M. Tato, Arian Laurence et al. · Nature Immunology · 2009 · 1.1K citations · Full text

, , +17

A Human Interleukin-12/23 Monoclonal Antibody for the Treatment of Psoriasis

Gerald G. Krueger, Richard G. Langley, Craig L. Leonardi et al. · New England Journal of Medicine · 2007 · 785 citations · Full text

, , +17

A Randomized Trial of Ustekinumab, a Human Interleukin-12/23 Monoclonal Antibody, in Patients With Moderate-to-Severe Crohn's Disease

William J. Sandborn, Brian G. Feagan, Richard N. Fedorak et al. · Gastroenterology · 2008 · 746 citations · Full text

, , +16

Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial

Alice B. Gottlieb, Alan Menter, Alan M. Mendelsohn et al. · The Lancet · 2009 · 583 citations

, , +15

CD40 regulates the processing of NF‐κB2 p100 to p52

Horspool Coope · The EMBO Journal · 2002 · 442 citations · Full text

, , +6