Concepedia

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING

Christian K. Holm, Søren B. Jensen, Martin R. Jakobsen, Natalia Cheshenko, Kristy Horan, Hanne B. Moeller, Regina Gonzalez‐Dosal, Simon Rasmussen, Maria H. Christensen, Timur O. Yarovinsky,

Nature Immunology · 2012 · 242 citations · 24 references

DOI

Concepts

References

24

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.6K citations · Full text

, , +11

IFI16 is an innate immune sensor for intracellular DNA

Leonie Unterholzner, Sinéad E. Keating, Marcin Baran et al. · Nature Immunology · 2010 · 1.6K citations · Full text

, , +14

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

Zhiqiang Zhang, Bin Yuan, Musheng Bao et al. · Nature Immunology · 2011 · 868 citations

, , +9