Martin R. Jakobsen

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Gillian Dunphy, Sinéad Flannery, Jessica F. Almine et al. · Molecular Cell · 2018 · 621 citations · Full text

Attenuation of c <scp>GAS</scp> ‐ <scp>STING</scp> signaling is mediated by a p62/ <scp>SQSTM</scp> 1‐dependent autophagy pathway activated by TBK1

Thaneas Prabakaran, Chiranjeevi Bodda, Christian Krapp et al. · The EMBO Journal · 2018 · 451 citations · Full text

Cell Autophagy, Transcriptional Regulation, Mitophagy +13

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

David Olagnier, Ensieh Farahani, Jacob Thyrsted et al. · Nature Communications · 2020 · 444 citations · Full text

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Martin R. Jakobsen, Rasmus O. Bak, Annika Andersen et al. · Proceedings of the National Academy of Sciences · 2013 · 332 citations · Full text

Lentiviral Replication Cycle, Viral Replication, Immunology +21

<scp>cGAS</scp> is activated by <scp>DNA</scp> in a length‐dependent manner

Stefanie Luecke, Andreas Holleufer, Maria H. Christensen et al. · EMBO Reports · 2017 · 282 citations · Full text

Chromatin, Transcriptional Regulation, Natural Sciences +9