Sinéad Flannery

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Gillian Dunphy, Sinéad Flannery, Jessica F. Almine et al. · Molecular Cell · 2018 · 621 citations · Full text

Human Interleukin-1 Receptor-associated Kinase-2 Is Essential for Toll-like Receptor-mediated Transcriptional and Post-transcriptional Regulation of Tumor Necrosis Factor α

Sinéad Flannery, Sinéad E. Keating, Joanna Szymak et al. · Journal of Biological Chemistry · 2011 · 34 citations · Full text

Early Tlr, Innate Immune System, Immune Regulation +21

A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance

Hui Wang, Souhayla El Maadidi, Janett Fischer et al. · Hepatology · 2015 · 26 citations

A Coding IRAK2 Protein Variant Compromises Toll-like receptor (TLR) Signaling and Is Associated with Colorectal Cancer Survival

Hui Wang, Sinéad Flannery, Sabine Dickhöfer et al. · Journal of Biological Chemistry · 2014 · 21 citations · Full text

Poxviral Protein A52 Stimulates p38 Mitogen-activated Protein Kinase (MAPK) Activation by Causing Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Self-association Leading to Transforming Growth Factor β-activated Kinase 1 (TAK1) Recruitment

Julianne Stack, Tara Hurst, Sinéad Flannery et al. · Journal of Biological Chemistry · 2013 · 19 citations · Full text

P38 Activation, Immunology, Immune Regulation +20