Concepedia

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

Zhiqiang Zhang, Bin Yuan, Musheng Bao, Ning Lü, Tae Il Kim, Yong‐Jun Liu

Nature Immunology · 2011 · 868 citations · 24 references

DOI

Concepts

References

24

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature · 2006 · 3.8K citations

, , +12

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

, , +12

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.6K citations · Full text

, , +11

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Teresa Fernandes‐Alnemri, Je‐Wook Yu, Pinaki Datta et al. · Nature · 2009 · 1.8K citations · Full text

, , +12