Concepedia

Helicase Function

Helicase Function is the enzymatic process by which ATP-dependent helicase enzymes catalyze the unwinding of double-stranded DNA into single strands during DNA replication, thereby enabling template access for polymerases.

3.2K

Publications

242.7K

Citations

9.2K

Authors

1.6K

Institutions

Publications per year

2017–2026

483

Parents

Children

Publications

3.2K

The Bloom's syndrome gene product is homologous to RecQ helicases

Nathan A. Ellis, Joanna Groden, Tian-Zhang Ye et al. · Cell · 1995 · 1.4K citations · Full text

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DNA gyrase: an enzyme that introduces superhelical turns into DNA.

Martin Gellert, Kiyoshi Mizuuchi, M H O'Dea et al. · Proceedings of the National Academy of Sciences · 1976 · 1.2K citations · Full text

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Helicases: amino acid sequence comparisons and structure-function relationships

Alexander E. Gorbalenya, Eugene V. Koonin · Current Opinion in Structural Biology · 1993 · 1.2K citations

, , +14

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

Leonard Wu, Ian D. Hickson · Nature · 2003 · 1.1K citations

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Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

Zhu Zhu, Woo-Hyun Chung, Eun Yong Shim et al. · Cell · 2008 · 1K citations · Full text

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1–5 of 3.2K

Authors

9.2K

  1. TM
    Timothy M. Lohman

    Washington University in St. Louis, United States

    52 publications · 4.9K citations

    36

    h-index

  2. RM
    Robert M. Brosh

    National Institute on Aging, United States

    46 publications · 3.9K citations

    35

    h-index

  3. SW
    Steven W. Matson

    University of North Carolina at Chapel Hill, United States

    36 publications · 2.7K citations

    28

    h-index

  4. CC
    Charles C. Richardson

    Harvard University, United States

    42 publications · 2.3K citations

    28

    h-index

  5. SS
    Smita S. Patel

    Johnson University, United States

    40 publications · 2.5K citations

    28

    h-index

1–5 of 9.2K

Institutions

1.6K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    68 h-index

    242 publications

    38.9K citations

  2. Harvard University

    Cambridge, United States

    61 h-index

    393 publications

    50.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    60 h-index

    587 publications

    45.8K citations

  4. National Institutes of Health

    Bethesda, United States

    56 h-index

    352 publications

    34.8K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    46 h-index

    158 publications

    16.4K citations

  6. Yale University

    New Haven, United States

    42 h-index

    150 publications

    18K citations

  7. University of Oxford

    Oxford, United Kingdom

    42 h-index

    198 publications

    27.3K citations

  8. Washington University in St. Louis

    St Louis, United States

    41 h-index

    206 publications

    18K citations

1–8 of 1.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 602 publications · 41.4K citations

    107

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 192 publications · 20.5K citations

    86

    h-index

  3. Nucleic Acids Research

    400 publications · 22.2K citations

    75

    h-index

  4. The EMBO Journal

    86 publications · 11.9K citations

    65

    h-index

  5. Journal of Virology

    JVI · 138 publications · 9.8K citations

    64

    h-index

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