Helicase Pausing is a regulatory phenomenon in DNA metabolism wherein a helicase enzyme temporarily halts its unwinding activity along the nucleic acid substrate, distinguished from continuous translocation by its transient arrest that can influence replication fidelity, transcription coupling, and genome stability.
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DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase
Natalie M. Stano, Yong-Joo Jeong, Ilker Donmez et al. · Nature · 2005 · 178 citations · Full text
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International Centre for Genetic Engineering and Biotechnology, India
2 publications · 77 citations
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Howard Hughes Medical Institute
Chevy Chase, United States
3 h-index
4 publications
300 citations
Centre National de la Recherche Scientifique
Paris, France
3 h-index
4 publications
196 citations
National Institutes of Health
Bethesda, United States
3 h-index
10 publications
878 citations
University of Illinois Urbana-Champaign
Urbana, United States
2 h-index
5 publications
292 citations
Hutchison/MRC Research Centre
Cambridge, United Kingdom
2 h-index
9 publications
1.3K citations
Yale University
New Haven, United States
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5 publications
394 citations
MRC Cancer Unit
Cambridge, United Kingdom
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1.3K citations
The University of Tokyo
Tokyo, Japan
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3 publications
115 citations
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JBC · 10 publications · 594 citations
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- Molecular Cell
2 publications · 141 citations
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- Nucleic Acids Research
2 publications · 86 citations
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