Concepedia

Helicase Directionality

Helicase Directionality is the inherent biochemical property of a helicase enzyme that determines the specific polar orientation (5′→3′ or 3′→5′) along a nucleic acid strand in which it translocates to unwind duplex DNA or RNA during replication, repair, or transcription.

50

Publications

4.2K

Citations

159

Authors

62

Institutions

Publications per year

2017–2026

3

Parents

Publications

50

Running in Reverse: The Structural Basis for Translocation Polarity in Hexameric Helicases

N.D. Thomsen, James M. Berger · Cell · 2009 · 313 citations · Full text

, , +16

TWINKLE Has 5′ → 3′ DNA Helicase Activity and Is Specifically Stimulated by Mitochondrial Single-stranded DNA-binding Protein

Jenny Korhonen, Martina Gaspari, Maria Falkenberg · Journal of Biological Chemistry · 2003 · 300 citations · Full text

, , +17

The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)

C L Tai, W K, Ding‐Shinn Chen et al. · Journal of Virology · 1996 · 273 citations · Full text

, , +17

Escherichia coli helicase II (urvD gene product) translocates unidirectionally in a 3' to 5' direction.

Steven W. Matson · Journal of Biological Chemistry · 1986 · 212 citations · Full text

, , +9

The gene 4 protein of bacteriophage T7. Characterization of helicase activity.

Steven W. Matson, Stanley Tabor, C C Richardson · Journal of Biological Chemistry · 1983 · 211 citations · Full text

, , +17

1–5 of 50

Authors

159

  1. KD
    Kevin D. Raney

    University of Arkansas for Medical Sciences, United States

    6 publications · 324 citations

    6

    h-index

  2. RT
    Renu Tuteja

    International Centre for Genetic Engineering and Biotechnology, India

    3 publications · 70 citations

    3

    h-index

  3. AK
    Alicia K. Byrd

    University of Arkansas for Medical Sciences, United States

    3 publications · 216 citations

    3

    h-index

  4. CG
    Colin G. Wu

    Washington University in St. Louis, United States

    3 publications · 113 citations

    3

    h-index

  5. CE
    Craig E. Cameron

    Pennsylvania State University, United States

    3 publications · 106 citations

    3

    h-index

1–5 of 159

Institutions

62

  1. University of Arkansas for Medical Sciences

    Little Rock, United States

    5 h-index

    18 publications

    936 citations

  2. Kettering University

    Flint, United States

    4 h-index

    7 publications

    611 citations

  3. Pennsylvania State University

    State College, United States

    4 h-index

    12 publications

    632 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    7 publications

    839 citations

  5. International Centre for Genetic Engineering and Biotechnology

    New Delhi, India

    3 h-index

    9 publications

    188 citations

  6. University of Bristol

    Bristol, United Kingdom

    3 h-index

    5 publications

    195 citations

  7. University of Iowa

    Iowa City, United States

    2 h-index

    4 publications

    85 citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    4 publications

    458 citations

1–8 of 62

Venues

  1. Journal of Biological Chemistry

    JBC · 13 publications · 1.4K citations

    12

    h-index

  2. Cell

    5 publications · 780 citations

    5

    h-index

  3. Journal of Molecular Biology

    JMB · 5 publications · 397 citations

    5

    h-index

  4. Biochemistry

    5 publications · 180 citations

    5

    h-index

  5. Methods

    2 publications · 49 citations

    2

    h-index

1–5