Christian K. Holm

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

David Olagnier, Ensieh Farahani, Jacob Thyrsted et al. · Nature Communications · 2020 · 444 citations · Full text

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

Kasper L. Jønsson, Anders Laustsen, Christian Krapp et al. · Nature Communications · 2017 · 283 citations · Full text

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

Anne Louise Hansen, Gregory J. Buchan, Michael Rühl et al. · Proceedings of the National Academy of Sciences · 2018 · 278 citations · Full text

Immunology, Pathology, Inflammation +18

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

David Olagnier, Aske M. Brandtoft, Camilla Gunderstofte et al. · Nature Communications · 2018 · 269 citations · Full text

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING

Christian K. Holm, Søren B. Jensen, Martin R. Jakobsen et al. · Nature Immunology · 2012 · 235 citations · Full text

Innate Immunity Dependent, Adaptor Sting, Pathogenesis +9