Sulforaphane and α-Lipoic Acid Upregulate the Expression of the π Class of Glutathione S-Transferase through c-Jun and Nrf2 Activation

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

Peter Angel, Masayoshi Imagawa, Robert Chiu et al. · Cell · 1987 · 3K citations

Life Sciences, Biochemistry, Molecular Biology +14

Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

Bengt Mannervik, Per Ålin, Claes Guthenberg et al. · Proceedings of the National Academy of Sciences · 1985 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of <i>Helicobacter pylori</i> and prevents benzo[ <i>a</i> ]pyrene-induced stomach tumors

Jed W. Fahey, X. Haristoy, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2002 · 793 citations · Full text

Medicine, Microbiology, Pharmacology +16

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

Venugopal Radjendirane, Anil K. Jaiswal · Oncogene · 1998 · 565 citations

Life Sciences, Biochemistry, Cell Biology +14

Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis.

Kimihiko Satoh, Akio Kitahara, Yuki Soma et al. · Proceedings of the National Academy of Sciences · 1985 · 500 citations · Full text

Medicine, Biochemistry, Oncology +14