Concepedia

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

Vishal M. Gohil, Sunil A. Sheth, Roland Nilsson, Andrew P. Wojtovich, Jeong Hyun Lee, Fabiana Perocchi, William Chen, Clary B. Clish, Cenk Ayata, Paul S. Brookes,

Nature Biotechnology · 2010 · 351 citations · 32 references

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32

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht et al. · Genome biology · 2006 · 5.5K citations · Full text

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

, , +17

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Ralph J. DeBerardinis, Anthony Mancuso, Evgueni Daikhin et al. · Proceedings of the National Academy of Sciences · 2007 · 2.6K citations · Full text

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism · 2006 · 2.2K citations · Full text

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