Human and Rat Liver UDP-Glucuronosyltransferases Are Targets of Ketoprofen Acylglucuronide

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Birgit L. Coffman, Christopher D. King, Gladys R. Rios et al. · PubMed · 1998 · 326 citations

Medicine, Biochemistry, Pharmacology +13

The inadequacy of perinatal glucuronidation: immunoblot analysis of the developmental expression of individual UDP-glucuronosyltransferase isoenzymes in rat and human liver microsomes.

Michael W.H. Coughtrie, Brian Burchell, Julian E.A. Leakey et al. · Molecular Pharmacology · 1988 · 237 citations

Life Sciences, Biochemistry, Developmental Biology +13

Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family.

Thomas Ebner, Brian Burchell · Drug Metabolism and Disposition · 1993 · 206 citations

Life Sciences, Biochemistry, Molecular Biology +16

Covalent binding of zomepirac glucuronide to proteins: evidence for a Schiff base mechanism.

Philip C. Smith, Leslie Z. Benet, Antony F. McDonagh · Drug Metabolism and Disposition · 1990 · 124 citations

Pharmacy, Biochemistry, Pharmacology +16