Concepedia

Evaluation of 23 Lots of Commercially Available Cryopreserved Hepatocytes for Induction Assays of Human Cytochromes P450

Kanako Yajima, Yasuhiro Uno, Norie Murayama, Shotaro Uehara, Makiko Shimizu, Chika Nakamura, Kazuhide Iwasaki, Masahiro Utoh, Hiroshi Yamazaki

Drug Metabolism and Disposition · 2014 · 32 citations · 10 references

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References

10

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

, , +15

Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes

Ajay Madan, Richard Graham, Kathleen Carroll et al. · Drug Metabolism and Disposition · 2003 · 337 citations

, , +17

Induction of CYP2C genes in human hepatocytes in primary culture.

Sabine Gerbal‐Chaloin, Jean‐Marc Pascussi, Lydiane Pichard‐Garcia et al. · PubMed · 2001 · 318 citations

, , +15

Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines.

Thomas K. H. Chang, P Maurel, David J. Waxman · PubMed · 1997 · 195 citations

, , +16

Primary human hepatocytes as a tool for the evaluation of structure—activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin

Albert P. Li, Margaret Reith, John Gorski et al. · Chemico-Biological Interactions · 1997 · 170 citations

, , +14