Kanako Yajima

Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β₃-adrenoceptor agonist

Shin Takusagawa, Kanako Yajima, Aiji Miyashita et al. · Xenobiotica · 2012 · 48 citations

Evaluation of 23 Lots of Commercially Available Cryopreserved Hepatocytes for Induction Assays of Human Cytochromes P450

Kanako Yajima, Yasuhiro Uno, Norie Murayama et al. · Drug Metabolism and Disposition · 2014 · 32 citations

Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of the Pregnane X Receptor

Norie Murayama, Rinie van Beuningen, Hiroshi Suemizu et al. · Chemical Research in Toxicology · 2014 · 28 citations · Full text

Molecular Pharmacology, Pregnane X Receptor, Nuclear Receptor Conformation +15

Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine

Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki et al. · Drug Metabolism and Disposition · 2011 · 26 citations · Full text

Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies

Norie Murayama, Kanako Yajima, Mikiko Hikawa et al. · Biopharmaceutics & Drug Disposition · 2017 · 14 citations