Kanako Yajima

Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β₃-adrenoceptor agonist

Shin Takusagawa, Kanako Yajima, Aiji Miyashita et al. · Xenobiotica · 2012 · 48 citations

Medicine, Biochemistry, Pharmacology +17

Evaluation of 23 Lots of Commercially Available Cryopreserved Hepatocytes for Induction Assays of Human Cytochromes P450

Kanako Yajima, Yasuhiro Uno, Norie Murayama et al. · Drug Metabolism and Disposition · 2014 · 32 citations

Medicine, Pharmacology, Toxicology +16

Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of the Pregnane X Receptor

Norie Murayama, Rinie van Beuningen, Hiroshi Suemizu et al. · Chemical Research in Toxicology · 2014 · 28 citations · Full text

Medicine, Pharmacology, Toxicology +17

Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine

Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki et al. · Drug Metabolism and Disposition · 2011 · 26 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies

Norie Murayama, Kanako Yajima, Mikiko Hikawa et al. · Biopharmaceutics & Drug Disposition · 2017 · 15 citations

Pharmacy, Pharmacokinetics, Pharmacology +17