Concepedia

Author

Shin Takusagawa

Astellas Pharma (Japan)

Also Known As

Shin Takusagawa

17

Publications

375

Citations

9

H-Index

23

Concepts

All Affiliations

Astellas Pharma (Japan)Astellas Pharma (Netherlands)PharmAccess Group
ST

About

Shin Takusagawa is an author at Astellas Pharma (Japan) specializing in medicine, pharmacology, and pharmacotherapy.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

112

2

Biochemistry

1

1

39

3

Cell Biology

1

1

25

4

Cellular Physiology

1

1

25

5

Gastroenterology

1

1

25

Shin Takusagawa

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9

Publications

352

Citations

9

H-Index

YearCitations

Absorption, Metabolism and Excretion of [14C]Mirabegron (YM178), a Potent and Selective β3-Adrenoceptor Agonist, after Oral Administration to Healthy Male Volunteers

Shin Takusagawa, Jan Jaap van Lier, Katsuhiro Suzuki,

Drug Metabolism and Disposition

2012

62

<i>In vitro</i>inhibition and induction of human cytochrome P450 enzymes by mirabegron, a potent and selective β3-adrenoceptor agonist

Shin Takusagawa, Aiji Miyashita, Takafumi Iwatsubo,

Xenobiotica

2012

50

Development and validation of LC–MS/MS methods for the determination of mirabegron and its metabolites in human plasma and their application to a clinical pharmacokinetic study

Raymond van Teijlingen, John Meijer, Shin Takusagawa,

Journal of Chromatography B

2012

48

Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β<sub>3</sub>-adrenoceptor agonist

Shin Takusagawa, Kanako Yajima, Aiji Miyashita,

Xenobiotica

2012

48

Role of Cytochrome P450 Isoenzymes 3A and 2D6 in the In Vivo Metabolism of Mirabegron, a β3-Adrenoceptor Agonist

Jennifer Lee, Selina Moy, John Meijer,

Clinical Drug Investigation

2013

39

A novel plant nuclear gene encoding chloroplast ribosomal protein S9 has a transit peptide related to that of rice chloroplast ribosomal protein L12

Shin‐ichi Arimura, Shin Takusagawa, Shoji Hatano,

FEBS Letters

1999

30

Pharmacokinetics of Mirabegron, a β3-Adrenoceptor Agonist for Treatment of Overactive Bladder, in Healthy Japanese Male Subjects: Results from Single- and Multiple-Dose Studies

Hiromi Iitsuka, Tomoaki Tokuno, Yoko Amada,

Clinical Drug Investigation

2013

30

Intestinal Absorption Mechanism of Mirabegron, a Potent and Selective β<sub>3</sub>-Adrenoceptor Agonist: Involvement of Human Efflux and/or Influx Transport Systems

Shin Takusagawa, Fumihiko Ushigome, Hiroyuki Nemoto,

Molecular Pharmaceutics

2013

25

Pharmacokinetics of Mirabegron, a β3-Adrenoceptor Agonist for Treatment of Overactive Bladder, in Healthy East Asian Subjects

Hiromi Iitsuka, Marcel van Gelderen, Masataka Katashima,

Clinical Therapeutics

2015

20

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