Concepedia

Role of Cytochrome P450 Isoenzymes 3A and 2D6 in the In Vivo Metabolism of Mirabegron, a β3-Adrenoceptor Agonist

Jennifer Lee, Selina Moy, John Meijer, Walter Krauwinkel, Taiji Sawamoto, Virginie Kerbusch, Donna Kowalski, Michael J. Roy, Alan Marion, Shin Takusagawa,

Clinical Drug Investigation · 2013 · 39 citations · 34 references

DOI

Concepts

References

34

The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype

Andrea Gaedigk, S.D. Simon, R PEARCE et al. · Clinical Pharmacology & Therapeutics · 2007 · 793 citations

, , +16

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

Shufeng Zhou · Clinical Pharmacokinetics · 2009 · 759 citations

, , +14

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

Markus H. Heim, Urs Meyer · The Lancet · 1990 · 451 citations

, , +7

Efficacy and Tolerability of Mirabegron, a β3-Adrenoceptor Agonist, in Patients with Overactive Bladder: Results from a Randomised European–Australian Phase 3 Trial

Vik Khullar, G. Amarenco, J.C. Angulo et al. · European Urology · 2012 · 425 citations

, , +14

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole

Klaus T. Olkkola, Janne T. Backman, Pertti J. Neuvonen · Clinical Pharmacology & Therapeutics · 1994 · 412 citations

, , +14