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Primary human hepatocytes as a tool for the evaluation of structure—activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin

Molecular PharmacologyBiochemistryMedicineLiver PhysiologyHepatotoxicityStructure—activity RelationshipMetabolismPharmacologyHuman MetabolismDrug-induced Liver InjuryToxicological MechanismDrug DiscoveryHealth Sciences