Role of a dipeptide insertion between codons 69 and 70 of HIV‐1 reverse transcriptase in the mechanism of AZT resistance

Rapid and simple method for purification of nucleic acids

René Boom, C. J. A. Sol, M M Salimans et al. · Journal of Clinical Microbiology · 1990 · 5.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +14

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

Life Sciences, Infectious Diseases, Analytical Chemistry +12

Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.

Paul Kellam, Charles A. Boucher, Brendan Larder · Proceedings of the National Academy of Sciences · 1992 · 420 citations

Life Sciences, Microbiology, Molecular Biology +17

Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

T Shirasaka, Mark F. Kavlick, Takamasa Ueno et al. · Proceedings of the National Academy of Sciences · 1995 · 390 citations

Life Sciences, Pharmacology, Molecular Virology +16

A Mechanism of AZT Resistance

Peter R. Meyer, S. Matsuura, A. Mohsin Mian et al. · Molecular Cell · 1999 · 343 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17