Concepedia

A Mechanism of AZT Resistance

Peter R. Meyer, S. Matsuura, A. Mohsin Mian, Antero G. So, Walter A. Scott

Molecular Cell · 1999 · 343 citations · 27 references

DOIFull text

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Concepts

References

27

HIV with Reduced Sensitivity to Zidovudine (AZT) Isolated During Prolonged Therapy

B. A. Larder, G. Darby, Douglas D. Richman · Science · 1989 · 1.6K citations

, , +17

Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance

Huifang Huang, Rajiv Chopra, Gregory L. Verdine et al. · Science · 1998 · 1.4K citations

, , +17

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

P A Furman, James A. Fyfe, M H St Clair et al. · Proceedings of the National Academy of Sciences · 1986 · 1.3K citations · Full text

, , +8

The "megaprimer" method of site-directed mutagenesis.

Gobinda Sarkar, S S Sommer · PubMed · 1990 · 1.2K citations

, , +12

The Accuracy of Reverse Transcriptase from HIV-1

John D. Roberts, Katarzyna Bębenek, Thomas A. Kunkel · Science · 1988 · 980 citations

, , +17