Concepedia

Resistance-associated Mutations

Resistance-Associated Mutations is a genomic construct denoting specific viral genetic variants that confer reduced susceptibility to antiviral agents by altering drug-target interactions or viral replication fitness in the context of drug resistance evolution.

5K

Publications

311.7K

Citations

26.7K

Authors

4.7K

Institutions

Publications per year

2017–2026

1.2K

Variants

Rams

Parents

Publications

5K

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

S. E. Luria, M. Delbrück · Genetics · 1943 · 3.9K citations

, , +17

Osimertinib or Platinum–Pemetrexed in <i>EGFR</i> T790M–Positive Lung Cancer

Tony Mok, Yi‐Long Wu, Myung‐Ju Ahn et al. · New England Journal of Medicine · 2016 · 3.3K citations · Full text

, , +16

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

Rong Liu, William A. Paxton, Sunny Choe et al. · Cell · 1996 · 3.1K citations · Full text

, , +13

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Michel Samson, Frédérick Libert, Benjamin J. Doranz et al. · Nature · 1996 · 2.9K citations

, , +11

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

, , +15

1–5 of 5K

Authors

26.7K

  1. RW
    Robert W. Shafer

    Stanford University, United States

    78 publications · 8.1K citations

    47

    h-index

  2. MA
    Mark A. Wainberg

    Jewish General Hospital, Canada

    110 publications · 6.4K citations

    43

    h-index

  3. BL
    Brendan Larder

    Wellcome Trust, United Kingdom

    48 publications · 7K citations

    38

    h-index

  4. VC
    Vincent Cálvez

    Sorbonne Université, France

    105 publications · 4.8K citations

    36

    h-index

  5. DR
    Daniel R. Kuritzkes

    Harvard University, United States

    55 publications · 5.1K citations

    36

    h-index

1–5 of 26.7K

Institutions

4.7K

  1. Harvard University

    Cambridge, United States

    67 h-index

    599 publications

    49.1K citations

  2. Inserm

    Paris, France

    57 h-index

    1.2K publications

    56.5K citations

  3. Stanford University

    Stanford, United States

    56 h-index

    466 publications

    45K citations

  4. National Institutes of Health

    Bethesda, United States

    51 h-index

    315 publications

    35.7K citations

  5. University College London

    London, United Kingdom

    48 h-index

    597 publications

    41.7K citations

  6. Sorbonne Université

    Paris, France

    46 h-index

    841 publications

    36.2K citations

  7. Johns Hopkins University

    Baltimore, United States

    46 h-index

    363 publications

    29.3K citations

  8. Jewish General Hospital

    Montreal, Canada

    45 h-index

    574 publications

    35K citations

1–8 of 4.7K

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 380 publications · 26.3K citations

    87

    h-index

  2. Journal of Virology

    JVI · 272 publications · 21.5K citations

    86

    h-index

  3. The Journal of Infectious Diseases

    JID · 210 publications · 17.5K citations

    77

    h-index

  4. AIDS

    260 publications · 16.4K citations

    71

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 62 publications · 9.4K citations

    54

    h-index

1–5