Concepedia

Identification of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70

Matthew K. Howe, Khaldon Bodoor, David A. Carlson, Philip F. Hughes, Yazan Alwarawrah, David R. Loiselle, Alex M. Jaeger, David B. Darr, Jamie L. Jordan, Lucas Hunter,

Chemistry & Biology · 2014 · 69 citations · 27 references

DOI

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References

27

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

Helen M. Beere, Beni B. Wolf, Kelvin Cain et al. · Nature Cell Biology · 2000 · 1.5K citations

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Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

Clayton R. Hunt, Ryo Morimoto · Proceedings of the National Academy of Sciences · 1985 · 872 citations · Full text

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Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility.

David J. Dix, James W. Allen, Bianca Collins et al. · Proceedings of the National Academy of Sciences · 1996 · 559 citations

, , +17

Fast docking using the CHARMM force field with EADock DSS

Aurélien Grosdidier, Vincent Zoete, Olivier Michielin · Journal of Computational Chemistry · 2011 · 506 citations

, , +17

A Small Molecule Inhibitor of Inducible Heat Shock Protein 70

Julia I-Ju Leu, Julia Pimkina, Amanda Frank et al. · Molecular Cell · 2009 · 444 citations · Full text

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