Concepedia
Statistics
Publications
75
Citations
8.8K
H-Index
44
Active since
1974
Affiliations
MRC Toxicology Unit(Current)
University of Leicester
Medical Research Council
University of Cambridge
University of Warwick
Kelvin Cain is an author at MRC Toxicology Unit specializing in life sciences, cell biology, and molecular biology.
Publications per year
1974–2023
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
Helen M. Beere, Beni B. Wolf, Kelvin Cain et al. · Nature Cell Biology · 2000 · 1.5K citations
Life Sciences, Cell Biology, Molecular Biology +16
cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
Maria Feoktistova, Peter Geserick, Beate Kellert et al. · Molecular Cell · 2011 · 849 citations · Full text
Life Sciences, Cell Biology, Molecular Biology +17
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
Tencho Tenev, Katiuscia Bianchi, Maurice Darding et al. · Molecular Cell · 2011 · 819 citations · Full text
Life Sciences, Cell Biology, Molecular Biology +8
A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death
Laura S. Dickens, Robert S. Boyd, Rebekah Jukes‐Jones et al. · Molecular Cell · 2012 · 335 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +17
Apaf-1 Oligomerizes into Biologically Active ∼700-kDa and Inactive ∼1.4-MDa Apoptosome Complexes
Kelvin Cain, Shawn B. Bratton, Claudia Langlais et al. · Journal of Biological Chemistry · 2000 · 315 citations · Full text
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