A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Vuk Stambolic, Akira Suzuki, José Luís de la Pompa et al. · Cell · 1998 · 2.5K citations · Full text

Tumor Biology, Signal Transduction, Signaling Pathway +12

COBRA: a sensitive and quantitative DNA methylation assay

Zhongguo Xiong, Peter W. Laird · Nucleic Acids Research · 1997 · 1.2K citations · Full text

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

Xinyi Wu, Kristen Senechal, Mehran S. Neshat et al. · Proceedings of the National Academy of Sciences · 1998 · 690 citations · Full text

Negative Regulator, Cancer Biology, Tumor Biology +16

Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation

Deborah J. Marsh · Human Molecular Genetics · 1998 · 658 citations · Full text

MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.

Dahong Teng, Rong Hu, Huai Lin et al. · PubMed · 1997 · 471 citations

Genetics, Pathology, Cancer Biology +17