Deborah Packham

MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer

Megan P. Hitchins, Rachel Williams, Kayfong Cheong et al. · Gastroenterology · 2005 · 198 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

<i>De novo</i> constitutional <i>MLH1</i> epimutations confer early‐onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

Ajay Goel, Thuy‐Phuong Nguyen, Hon‐Chiu Eastwood Leung et al. · International Journal of Cancer · 2010 · 92 citations · Full text

Life Sciences, Genetics, Oncology +17

Epigenetic Inactivation of a Cluster of Genes Flanking <i>MLH1</i> in Microsatellite-Unstable Colorectal Cancer

Megan P. Hitchins, Vita Ap Lin, Andrew Buckle et al. · Cancer Research · 2007 · 71 citations · Full text

Life Sciences, Genetics, Oncology +17

Mosaic Epigenetic Inheritance as a Cause of Early-Onset Colorectal Cancer

Mathew A. Sloane, Andrea C. Nunez, Deborah Packham et al. · JAMA Oncology · 2015 · 55 citations

Medicine, Genetics, Oncology +17

Lynch Syndrome Associated with Two <i>MLH1</i> Promoter Variants and Allelic Imbalance of <i>MLH1</i> Expression

Luke B. Hesson, Deborah Packham, Chau‐To Kwok et al. · Human Mutation · 2015 · 54 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17