Deborah Packham

MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer

Megan P. Hitchins, Rachel Williams, Kayfong Cheong et al. · Gastroenterology · 2005 · 195 citations · Full text

Medicine, Genetics, Colorectal Cancer +6

<i>De novo</i> constitutional <i>MLH1</i> epimutations confer early‐onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

Ajay Goel, Thuy‐Phuong Nguyen, Hon‐Chiu Eastwood Leung et al. · International Journal of Cancer · 2010 · 91 citations · Full text

Paternal Allele, Cancer Pathology, Genetics +16

Epigenetic Inactivation of a Cluster of Genes Flanking <i>MLH1</i> in Microsatellite-Unstable Colorectal Cancer

Megan P. Hitchins, Vita Ap Lin, Andrew Buckle et al. · Cancer Research · 2007 · 71 citations · Full text

Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified

Robyn L. Ward, Rachel Williams, Brita Pekarsky et al. · The Journal of Pathology · 2005 · 54 citations · Full text

Lynch Syndrome Associated with Two <i>MLH1</i> Promoter Variants and Allelic Imbalance of <i>MLH1</i> Expression

Luke B. Hesson, Deborah Packham, Chau‐To Kwok et al. · Human Mutation · 2015 · 53 citations · Full text

Genetics, Pathology, Molecular Genetics +17