Chau‐To Kwok

Dominantly Inherited Constitutional Epigenetic Silencing of MLH1 in a Cancer-Affected Family Is Linked to a Single Nucleotide Variant within the 5′UTR

Megan P. Hitchins, Robert W. Rapkins, Chau‐To Kwok et al. · Cancer Cell · 2011 · 194 citations · Full text

Chromatin, Genome Instability, Constitutional Epigenetic Silencing +13

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment

Justin Wong, Dadi Gao, Trung Viet Nguyen et al. · Nature Communications · 2017 · 110 citations · Full text

<i>De novo</i> constitutional <i>MLH1</i> epimutations confer early‐onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

Ajay Goel, Thuy‐Phuong Nguyen, Hon‐Chiu Eastwood Leung et al. · International Journal of Cancer · 2010 · 91 citations · Full text

Paternal Allele, Cancer Pathology, Genetics +16

Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

Immanuel D Green, Natalia Pinello, Renhua Song et al. · Nucleic Acids Research · 2020 · 80 citations · Full text

Innate Immune System, Immunology, Immune Regulation +20

Epigenetic Inactivation of a Cluster of Genes Flanking <i>MLH1</i> in Microsatellite-Unstable Colorectal Cancer

Megan P. Hitchins, Vita Ap Lin, Andrew Buckle et al. · Cancer Research · 2007 · 71 citations · Full text