Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

Sandra Navarra, Renato Guzmán, A Gallacher, +13

The Lancet

RheumatologyAutoimmune DiseaseLupusSystemic TreatmentLupus Nephritis +4

TACI-Ig Neutralizes Molecules Critical for B Cell Development and Autoimmune Disease

Jane A. Gross, Stacey R. Dillon, Sherri Mudri, +15

Immunity

ImmunogeneticsSignal TransductionAutoimmune DiseaseImmune Cell DevelopmentImmunology +9

A phase II, randomized, double‐blind, placebo‐controlled, dose‐ranging study of belimumab in patients with active systemic lupus erythematosus

Daniel J. Wallace, William Stohl, Richard Furie, +11

Arthritis Care & Research

APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth

Michael Hahne, Takao Kataoka, Michael Schröter, +10

The Journal of Experimental Medicine

InflammationCytokineTumor Necrosis FactorTumor GrowthApoptosis +12

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

Micah J. Benson, Stacey R. Dillon, Emanuela Castigli, +4

The Journal of Immunology

Impaired IgA class switching in APRIL-deficient mice

Emanuela Castigli, Sumi Scott, Fatma Dedeoğlu, +5

Proceedings of the National Academy of Sciences

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

Elodie Belnoue, Maria Pihlgren, Tracy L. McGaha, +7

Blood

Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: Results of a multicenter, phase ib, double‐blind, placebo‐controlled, dose‐escalating trial

Maria Dall’Era, Eliza F. Chakravarty, Daniel J. Wallace, +8

Arthritis & Rheumatism

BLyS and APRIL in rheumatoid arthritis

Thorsten M. Seyler

Journal of Clinical Investigation

Humoral ResponseImmunologyImmune RegulationB Cell ActivationImmunologic Mechanism +17

APRIL modulates B and T cell immunity

Jens V. Stein, Marta López‐Fraga, Fernando A. Elustondo, +7

Journal of Clinical Investigation

InflammationApril Mrna ExpressionB Cell HomeostasisAutoimmune DiseaseAllergy +13